Meryl Streep, Academy Award winner (Supporting Actress 1979, Best Actress 1982 and 2011). Nominated for Best Actress in 1981, 1983, 1985, 1987, 1988, 1990, 1995, 1998, 1999, 2006, 2008, 2009, and 2013. For Best Supporting Actress in 1978 and 2002
Michelle Obama & Meryl Streep On Raising Strong Daughters
How Michelle Obama & Meryl Streep have raised strong, confident daughters
Though not a Dame I will place this in Great Dames as if Meryl was a Brit she'd certainly have this honour.
Miranda Priestly. This fictional style icon was portrayed by Meryl Streep in The Devil Wears Prada, one of my all-time favourite fashion-centred films. She was fierce from head to toe scene after scene.